Fmoc-Ala-Ala-OH is a Fmoc-protected alanine derivative for use in proteomics research and solid-phase peptide synthesis techniques. Alanine is one of the simplest amino acids with a methyl side chain. This small side chain is highly flexible (second only to glycine) for incorporation into peptide chains. The Fmoc group is usually removed with a base such as pyridine, a deprotection strategy orthogonal to the acidic Labilie Boc group. It consists of two L-alanine molecules linked together by a peptide bond, with a protecting group (Fmoc) attached to the N-terminal amino acid. The Fmoc group provides stability and protection during peptide synthesis, and can be easily removed, exposing the free amino group for further reactions.
