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网站主页 PROGRAMMED CELL DEATH 1 LIGAND 1/PD-L1 PROTEIN Programmed cell death 1 ligand 1/PD-L1 protein
  • Programmed cell death 1 ligand 1/PD-L1 protein

Programmed cell death 1 ligand 1/PD-L1 protein

Recombinant human Programmed cell death 1 ligand 1/PD-L1 protein
630 10ug 起订
2730 100ug 起订
上海 更新日期:2023-10-16

爱必信(上海)生物科技有限公司

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产品详情:

中文名称:
Programmed cell death 1 ligand 1/PD-L1 protein
英文名称:
Recombinant human Programmed cell death 1 ligand 1/PD-L1 protein
产品类别:
重组蛋白

 

产品描述:

产品名称:Recombinant human Programmed cell death 1 ligand 1/PD-L1 protein

产品别名:CD274

形态:Protein is supplied in 20 mM Tris,150 mM NaCl, 10% Glycerol, pH 7.5

氨基酸序列:见爱必信官网

内毒素水平:见爱必信官网

活性:见爱必信官网

保存方法:Clear solution, frozen.Store at -70°C. At first use, aliquot and store at -70°C to avoid multiple freeze-thaws.

产品描述:

Recombinant human PD-L1 protein aa 1-238 was produced in mammalian cells with C-terminal His-DYK tag. The theoretical molecular weight of recombinant PD-L1 is 27.3 kDa. Purified PD-L1 protein is near the position of 34 kDa on SDS-PAGE gel under reduced condition.
PD-L1 protein is purified by proprietary chromatographic techniques. 

Entrez Gene summary for PD-L1:

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma.

UniProtKB/Swiss-Prot: Q9NZQ7 (PD1L1_HUMAN)

Function: Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.

 

预期分子量:见爱必信官网

 

产品信息订购:

  产品货号
  产品名称
  规格
价格
大包装及货期
  abs02002
  Recombinant human Programmed cell death 1 ligand 1/PD-L1 protein
  10ug
  600
  立即咨询

产品更多信息请进入爱必信网站咨询

Programmed cell death 1 ligand 1/PD-L1 protein;重组蛋白PD-L1

公司简介

爱必信(上海)生物科技有限公司成立于2010年,位于上海市申江科创园。是一家自主研发和生产生物试剂的公司。 Absin?是爱必信(上海)生物科技有限公司的试剂品牌,目前已近60万种生化试剂,10万种抗体,其基础生化试剂在基础科学领域得到广泛应用的同时,特色产品线常规生化试剂,血清,小分子激动剂及抑制剂在业界也备受好评。 Absin秉承踏实,务实,求精和不断创新的精神为中国科学家提供最好的产品,努力打造属于中国自己的生物试剂品牌,为广大科学家提供更全面更丰富更优质的产品。 爱科研,必信它(Absin)!Absin努力成为你身边的科研百宝箱!

成立日期 (14年)
注册资本 2500万
员工人数 100-500人
年营业额 ¥ 1000万-5000万
经营模式 工厂
主营行业 生化试剂,抗体,分子生物学,生物活性小分子

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