Lubricant; transformer oil. Anti-corrosion agent. Biological marker. In experimental systems to induce plasmacytomas; in production of monoclonal antibodies.
Pristane is a hydrocarbon oil adjuvant.
Pristane has been used as an inflammation-inducing agent, leading to myeloma development in BALB/c strain mice. It has been used as a rheumatoid arthritis-inducing agent in rats.
ChEBI: A norterpene that is an acyclic saturated hydrocarbon derived from phytane by loss of its C-16 terminal methyl group.
Pristane is a natural saturated terpenoid alkane used in research on the pathogenesis of autoimmune diseases such as arthritis and lupus.
Pristane is a hydrocarbon oil adjuvant widely used to induce tumorigenesis in mice and arthritis and lupus nephritis in rats. It works as a adjuvant for monoclonal antibody generation in mouse ascites.
Purify pristane by shaking it with conc H2SO4 (care, if amount of pristane is too small then it should be diluted with pet ether not Et2O which is quite soluble H2SO4), then H2O (care, as it may heat up in contact with conc H2SO4), dry (MgSO4), evaporate and distil it over Na. [S.rensen & S.rensen Acta Chem Scand 3 939 1949, Beilstein 1 III 570.]
