Antagonist (cholecystokinin).
Devazepide has been used as a cholecystokinin receptor 1 (CCK1R) antagonist in human embryonic kidney 293T cells and in human pancreatic slices.
ChEBI: An indolecarboxamide obtained by formal condensation of the carboxy group of indole-2-carboxylic acid with the exocyclic amino group of (3S)-3-amino-1-methyl-5-phenyl-1,3-dihydro-1,4-benzodiazepin-2-one. A cholecystokinin antagonist used f
r treatment of gastrointestinal disorders.
Devazepide is derived from asperlicin by chemical modification and has the benzodiazepine backbone.
Devazepide is a CCK1 (CCK-A) receptor antagonist and a CCK8 antagonist.
