≥25.05 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form
solid
pka
14.25±0.46(Predicted)
color
White to yellow
Safety Information
RIDADR
3077
HS Code
29341000
Usage And Synthesis
Description
LCL-161 is a small molecule Smac mimetic that inhibits multiple inhibitor of apoptosis (IAP) family proteins.
Uses
LCL 161 is a second mitochondria-derived activator of caspases (SMAC) inhibitor used to prolong patient survival by increasing apoptosis of anti-tumor drugs.
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