盐酸特拉唑嗪
盐酸特拉唑嗪 性质
| 沸点 | 664.5±65.0 °C(Predicted) |
|---|---|
| 密度 | 1.332±0.06 g/cm3(Predicted) |
| 储存条件 | Store at -20°C |
| 溶解度 | 二甲基亚砜：75 mg/mL（193.58 mM） |
| 形态 | 固体 |
| 酸度系数(pKa) | 6.52±0.50(Predicted) |
| 颜色 | 白色至米白色 |
盐酸特拉唑嗪 用途与合成方法
Ki: 6.51 nM (α1a-adrenoceptor), 1.01 nM (α1b-adrenoceptor) and 1.97 nM (α1d-adrenoceptor)
(R)-Terazosin is low affinity for α2a, α2B and α2c-adrenoceptor with K
i
values of 3.85 μM, 0.33 μM and 0.37 μM, respectively.
(R)-Terazosin may prove to be a useful probe in understanding the functional role of subtypes of adrenoceptors in various tissues. Because it is a weaker antagonist at α2B sites than its enantiomer, it may be possible to use (R)-Terazosin to differentiate between pharmacological effects mediated by subtypes of α2-adrenoceptors in animal studies.
(R)-Terazosin shows antagonism of at rat atrial α2B receptor with a pEC 30 of 5.69. (R)-Terazosin shows antagonism of at rat vas deferens α1A and α2A receptor with pA 2 values of 7.5 and 5.31, respectively.
盐酸特拉唑嗪 价格(试剂级)
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2024-08-19 | HY-B0371B | 盐酸特拉唑嗪 | 109351-34-0 | 5mg | 2000 |
| 2024-08-19 | HY-B0371B | 盐酸特拉唑嗪 | 109351-34-0 | 10mM * 1mLin DMSO | 2200 |
