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Febrifugine Structure

Febrifugine

Chemical Properties

Melting point 139-140°; mp 154-156°
alpha  D25 +6° (c = 0.5 in chloroform); D25 +28° (c = 0.5 in ethanol)
Density  1.39
storage temp.  2-8°C
solubility  DMF: 1.5 mg/ml; DMSO: 3.0 mg/ml; Ethanol: 0.1 mg/ml; PBS (pH 7.2): 2.5 mg/ml
form  A crystalline solid
Boiling point 508.2±60.0 °C(Predicted)
pka 14.61±0.40(Predicted)
color  White to off-white
CAS DataBase Reference 24159-07-7

Safety Information

Toxicity LD50 orally in white mice: 2.5-3.0 mg/kg (Koepfli, 1949)

Usage And Synthesis

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