Uses
Antiulcerative;M1 muscarinic antagonist
Uses
Telenzepine dihydrochloride is a potent and selective muscarnic receptor antagonist.
Uses
Telenzepine dihydrochloride hydrate was used to study M
1 muscarinic receptor-mediated signaling in juvenile rat hippocampus and rat urinary bladder.
Biological Activity
Selective high affinity muscarinic M 1 receptor antagonist (K i = 0.94 nM). Inhibits gastric acid secretion.
Biochem/physiol Actions
Telenzepine is an analog of pirenzepine and inhibits the secretion of gastric acid. It is an antagonist to M1-receptor and targets the oxyntic gastric glands and the salivary glands.
