Chemical Properties
clear colorless to slightly yellow liquid
Uses
Methyl 2-Oxocyclohexanecarboxylate is a novel intermediate for the preparation of TRPA1 antagonists for treatment of pain and other TRPA1-associated diseases.
Uses
Methyl 2-oxocyclohexanecarboxylate has been used in the synthesis of substituted tetrahydrobenzofuran derivatives via reaction with propargylic esters in the presence of palladium catalyst.
Synthesis Reference(s)
Journal of the American Chemical Society, 102, p. 431, 1980
DOI: 10.1021/ja00521a100Organic Syntheses, Coll. Vol. 7, p. 351, 1990