BAX 抗体

保存条件:-20*C
浓度:0.3 mg/ml
应用范围:ELISA, WB
适应物种: 人动物植物
宿主:Rabbit
抗体英文名:Anti-BAX antibody
保质期:12个月
克隆性:多克隆
数量:大量
供应商:上海机纯实业有限公司
规格:25 μ/100 uμ/200 μl
Anti-BAX antibody
Cat. No. JC120073
Package 25 μI/100 μl/200 μl
Storage -20*C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description
Anti-BAX rabbit polyclonal antibody
Applications
ELISA, WB
Immunogen
Fusion protein of human BAX
Reactivity
Human, Mouse, Rat
Content
0.3 mg/ml
Host species
Rabbit
lg class
Immunogen-specific rabbit lgG
Purification
Antigen afinity purification
Anti-BAX antibody
Target information
Symbol BAX
Full name BCL 2-associated X protein
Synonyms BCL2L4 Swissprot Q07812

Target Background
The protein encoded by this gene belongs to the BCL _2 protein family. BCL _2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This
protein forms a heterodimer with BCL 2; and functions as an apoptotic activator. This protein is reported to interact with,
and increase the opening of. the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in
membrane potential and the release of cytochrome C. The expression of this gene is regulated by the tumor
suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript
variants, which encode diferent isoforms, have been reported for this gene.
Anti-BAX antibody
Applications
Western blotting
Predicted band size:21 kDa
Positive control:Human brain malignant glioma tissue, MCF7 Raji, Lovo and 293T cells
Recommended dilution: 500-2000