麻痹肽神经毒素多肽α-Conotoxin GID/547741-78-6/α-Conotoxin GID

Product Name：α-Conotoxin GID

CAS No.：547741-78-6

Synonyms：麻痹肽神经毒素多肽α-Conotoxin GID

Catalog No.：218P939

Brand：HongTide（上海鸿肽生物）

Description：α-Conotoxin GID 是一种麻痹肽神经毒素，是由19个氨基酸组成的环状多肽，是 nAChR 的选择性拮抗剂，IC50 为 5 nM (α7)、3 nM (α3β2)，150 nM (α4β2)。α-Conotoxin GID 是一种富含二硫键的小肽，具有抑制慢性疼痛的潜力。α-Conotoxin GID 含有 C 端羧酸酯，因此用 C 端羧酰胺取代会导致 α4β2 nAChR 丢失。α-Conotoxin GID 可以从芋螺属物种中分离出来。

Alpha Notoxin GID is a numbing peptide neurotoxin composed of a cyclic peptide of 19 amino acids. It is a selective antagonist of nAChR with IC50 values of 5 nM (α 7), 3 nM (α 3 β 2), and 150 nM (α 4 β 2). Alpha Notoxin GID is a small peptide rich in disulfide bonds that has the potential to inhibit chronic pain. The α - Coronation GID contains a C-terminal carboxylic acid ester, so replacing it with a C-terminal carboxylic acid amide will result in the loss of α 4 β 2 nAChR. The α - Notoxin GID can be isolated from species of the Conus genus.

Purity (HPLC) ≥98.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Solubility：H₂O/DMSO

Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.

订购联系方式：

上海鸿肽生物科技有限公司

手机： +86-18018095145 （同微信号）

QQ: 3259098395

邮箱：sales1@hongtide.com