红曲色素,21516-68-7

别名

单子叶黄素,（3,3a,9a）-3-己酰基-9a-甲基-6-（（）-丙烯基）3a,4,8,9a-四氢-3氢-呋喃并[3,2-g]异染色质-2,9-二酮,（3,3a,9a）-3a,4,8,9a-四氢-9a-甲基-3-（1-氧代己基）-6-（1E）-1-丙烯基-2氢-呋喃[3,2-g][2]苯并吡喃-2,9（3氢）-二酮

一般描述

Monascin is one of the major yellow pigments found in red mold rice. It is structurally similar to ankaflavin.

应用

Monascin has been used to treat 4T1 breast cancer cells and to test its effects on tumor cells anoikis and growth prevention.

生化/生理作用

Monascin (MS) exerts anti-diabetic and antioxidant properties and provides hyperglycemia control, tissue protection, and thermotolerance in diabetic rats and C. elegans, respectively. It also displays antitumor activity and inhibits Alzheimer′s disease-related tau protein aggregation. Monascin up-regulates high-density lipoprotein cholesterol (HDL-C) levels in hyperlipidemic hamsters model and possesses hypolipidemic properties. It may also possess hepatoprotective effects. 红曲色素是红曲-发酵米（红霉米）提取物中的氮杂类色素之一。它是针对化学或紫外线引发的佛波醇促进的小鼠皮肤肿瘤测量的致癌作用的有效抑制剂。