血小板反应蛋白抑制剂(TSP-1)/162559-45-7/LSKL, Inhibitor of Thrombospondin (TSP-1)

Product Name：LSKL, Inhibitor of Thrombospondin (TSP-1)

CAS No.：162559-45-7

Synonyms：血小板反应蛋白抑制剂(TSP-1)

Catalog No.：209P02

Brand：HongTide（上海鸿肽生物）

Description：LSKL, Inhibitor of Thrombospondin (TSP-1)是一种衍生自 LAP-TGFβ 的四肽，是一种竞争性的 TGF-β1 拮抗剂。LSKL, Inhibitor of Thrombospondin (TSP-1)抑制 TSP-1 与 LAP 的结合并减轻肾间质纤维化和肝纤维化。LSKL, Inhibitor of Thrombospondin (TSP-1)通过抑制 TSP-1 介导的 TGF-β1 活性来抑制蛛网膜下纤维化，防止慢性脑积水的发生并改善蛛网膜下腔出血后的长期神经认知缺陷。LSKL, Inhibitor of Thrombospondin (TSP-1)可以轻松穿越血脑屏障。

LSKL, Inhibitor of Thrombospondin (TSP-1) is a derivative of LAP-TGF β  Tetrapeptide, a competitive TGF- β 1 Antagonist. LSKL, Inhibitor of Thrombospondin (TSP-1), inhibits the binding of TSP-1 to LAP and alleviates renal interstitial fibrosis and liver fibrosis. LSKL, Inhibitor of Thrombospondin (TSP-1) inhibits TSP-1 mediated TGF- β 1 activity to inhibit subarachnoid fibrosis, prevent the occurrence of chronic hydrocephalus, and improve long-term neurocognitive deficits after subarachnoid hemorrhage. LSKL, Inhibitor of Thrombospondin (TSP-1), can easily cross the blood-brain barrier.

Purity (HPLC) ≥98.0%

Single impurity≤2%

Peptide content≥75.0%

Amino Acid Composition≤±15%

Bacterial Endotoxins≤50EU/mg

Solubility：H₂O/DMSO

Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.

Storage:Cool dry place( Store at -20°C, away from the light)

Remark:For Research Use Only. Not for human use.

Sequence(1-letter code)	LSKL
Sequence(3-letter code)	H-Leu-Ser-Lys-Leu-OH
Peptide Structure
Molecular Formula	C21H41N5O6
Molecular Weight	459.59

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