Name: Rifampicin
Synonyms: 3-[[(4-methyl-1-piperazinyl)imino]methyl]-rifamycin;3-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin SV;5,6,9,17,19,21-Hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-8-(N-(4-methyl-1-piperazinyl)formimidoyl)-2,7-(epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-1,11(2H)-dione 21-acetate;8-(4-Methylpiperazinyliminomethyl) rifamycin SV;
CAS Registry number: 13292-46-1
EINECS:236-312-0
Molecular Formula: C43H58N4O12
Boiling Point: 1004.42 °C at 760 mmHg
Flash Point: 561.253 °C
Density: 1.34 g/cm3
Appearance: Red to orange crystalline solid
Usage: Semisynthetic antibiotic. Antibacerial (tuberculostatic)
Safety Statements: S26;S36
Description:
Rifampin of rifamycin class semisynthetic broad-spectrum antibiotic, for a variety of pathogenic microorganisms. Antibacterial activity. The drug for mycobacterium tuberculosis and part of the mycobacterium tuberculosis (including leprosy mycobacteria, etc.) both inside and outside the host cells have obvious antiseptic effect. Rifampicin on aerobic gram positive bacteria have good antibacterial effect, including staphylococcus enzyme production strains and methicillin resistant strains, streptococcus pneumoniae, streptococcus, enterococcus other genera, listeria monocytogenes, bacillus anthracis, gas capsule bacillus, corynebacterium diphtheriae, anaerobic bacteria, etc. For aerobic gram-negative bacteria such as neisseria gonorrhoeae, h. influenzae, gonorrhea neisseria gonorrhoeae has high antibacterial activity. Rifampin of legionella bacteria effect also good, for chlamydia trachomatis, venereal disease is lymphatic granulation is swollen, psittacosis pathogens are inhibition, etc. Bacteria have cross resistance to rifamycin class antibiotics. Rifampicin and dependent on DNA, RNA polymerase beta subunit solid combination, inhibit bacterial RNA synthesis, prevent the enzyme connected with DNA, thereby blocking process of RNA transcription, DNA and protein synthesis.
Specification:
Tests | Specifications | Results |
Appearance | A bright-red, crystalline powder | Conforms |
Identification | A,B,C | Conforms |
PH | 4.5~6.5 | 5.5 |
Loss on drying | Not more than 1.0% | 0.8% |
Sulphated ash | Not more than 0.1% | 0.06% |
Heavy metals | Not more than 20ppm | 0.08ppm |
Bulk density (g/ml) | 0.5 | 0.52 |
Related substances Rifampicin quinone Any other impurity Total impurities | Not more than 1.5% Not more than 1.0% Not more than 3.5% | 0.5% 0.7% 2.1% |
Assay( 0n dry basis) | 97.0%~102.0% | 99.3% |
Rifampicin Application:
1. the product used in combination with other anti-TB drugs initial treatment and retreatment of various tuberculosis, including tuberculous meningitis treatment.
2. the product used in combination with other drugs leprosy, non-tuberculous mycobacterial infections.
3. The goods and vancomycin (intravenous) can be combined for methicillin resistant Staphylococcus aureus caused serious infections. Rifampicin and erythromycin joint programs can be used to Legionella serious infections.
4. for asymptomatic carriers of Neisseria meningitidis to eliminate Neisseria meningitidis nasopharynx; but not for Neisseria meningitidis infection.
Packaging & Shipping
FAQ
Q: How to start orders or make payments?A: You can send your requirement here on line,or send your purchase order by email to us, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.
Q: How to confirm the Product Quality before placing orders?A: You can buy samples for some products,and there will be discount for sample, after testing our sample, if all is ok for you, when make bulk order, we can return the sample fee back to you, and you can also send us your requirement for some special item, we can found for you in our local market.
Q: What's your MOQ?A: For the high value product, our MOQ starts from 1g and generally starts from 1kgs. For other low value product, our MOQ starts from 10kg and 100kg.
Q: Is there a discount?A: Different quantity has different discount, for larger quantity, we alway support with better price.
Q: How to contact us? A: You can chat with us by Whatsapp & Skype & wechat Online. You can also choose your interested products and send inquiry to us. You can dial our telephone directly, you will get our reply. Send Email to us.
Company Profile
Hebei Ningnan Trade Co., Ltd. located in Shijiazhuang City, Hebei Province, is a large enterprise specializing in production and R & D. Our company has many years of export experience in this industry and professional logistics distribution.
We have many production lines, including industrial chemicals, pharmaceutical chemicals, chemical raw materials, fine chemicals and customized synthetic products.
We have a professional R & D team. Products are widely used in industry, rubber, textile, pharmaceutical and other industries. Products are exported to Europe, America, Southeast Asia and other countries. New and old customers are welcome to negotiate business.
China
