Product Description
Specification:
Product Name | Candesartan cilexetil |
CAS No. | 145040-37-5 |
EINECS No. | 627-030-2 |
MF | C33H34N6O6 |
MW | 610.66 |
Purity | 99%min |
Storage | 2-8°C |
Boiling point | 843.3±75.0 °C(Predicted) |
Density | 1.37±0.1 g/cm3(Predicted) |
solubility | DMSO: ≥15mg/mL |
Type | Pharmaceutical Intermediates |
Quality | Refined |
Package | 25kg/bag |
Shelf life | 2 years |
Application:
Candesartan cilexetil is a prodrug of the potent, long-acting, and selective angiotensin II type 1 receptor AT1 antagonist, candesartan. It is rapidly hydrolyzed to candesartan during gastrointestinal absorption. After hydrolysis of candesartan cilexetil to candesartan during gastrointestinal absorption, candesartan selectively competes with angiotensin II for the binding of the angiotensin II receptor subtype 1 AT1 in vascular smooth muscle, blocking angiotensin II-mediated vasoconstriction and inducing vasodilatation. In addition, antagonism of AT1 in the adrenal gland inhibits angiotensin II-stimulated aldosterone synthesis and secretion by the adrenal cortex; sodium and water excretion increase, followed by a reduction in plasma volume and blood pressure.
Candesartan cilexetil can be used as pesticide and pharmaceutical intermediates.
It can be used as the raw material of antihypertensive drugs.
Candesartan is an angiotensin-receptor blocker (ARB)，Angiotensin receptor blockers effectively protect against the harmful effects of the activation of the renin-angiotensin-aldosterone system that occur with hypertension or diabetes.It may be used alone or with other agents to treat hypertension. Unlike angiotensin-converting enzyme (ACE) inhibitors, ARBs do not have the adverse effect of dry cough.
Candesartan may be used to treat hypertension, isolated systolic hypertension, left ventricular hypertrophy and diabetic nephropathy. It may also be used as an alternative agent for the treatment of heart failure, systolic dysfunction, myocardial infarction and coronary artery disease.
Anhui Ruihan Technology Co., Ltd.
Anhui Ruihan Technology Co., Ltd. is located in Hefei City, Anhui Province, China. It is specialized in the R&D, production and sales of pharmaceutical intermediates, cosmetic additives and food additives. It is a high-tech enterprise in China. Its products are widely used in the health industry, medical beauty, green agriculture, bio-medicine and other fields. Our scientific research team currently has more than 35 people, including 5 Doctors, 10 Masters, and 20 provincial-level high-level talents who have been introduced or trained. China Academy of Chinese Medical Sciences, Peking University Institute of Fine Chemicals, Southern University of Science and Technology and other scientific research institutes have established cooperative relations.
Our Advantages:
1. A strong scientific research team (35 people in the research team, including 5 Doctors, 10 Masters...).
2. Stable quality (with a complete scientific research center and testing center to ensure the quality stability of each batch of products).
3. Rich export experience (with practical experience in exporting to more than 30 countries such as North America, Europe, Middle East, and Southeast Asia).
4. Professional pre-sales and after-sales services (customer first is the core belief of our sales team).
5. Ability to provide value-added services (we can provide a wealth of product solutions to help customers improve competitiveness and production.
Packing&Shipping
FAQ:
Q1: How to start orders or make payments?
A1: You can send our your Purchase order(if your company has), or just send a simple confirmation by email or by Trade Manager, and we will send you Proforma Invoice with our bank details for your confirmation, then you can make payment accordingly.
Q2: How to confirm the Product Quality before placing orders?
A2: You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q3: Do you test all your goods before delivery?
A3: Yes, we have 100% test before delivery,International Authorized Third-Party Test for the products if you need are highly welcomed.
Q4: What's your MOQ?
A4: For the high value product, our MOQ starts from 1g and generally starts from 10gs. For other low price product, our MOQ starts
from 1kg.
Q5: Is there a discount?
A5: Yes, for larger quantity, we always support with better price.
Q6:How do you treat quality complaint?
A6: First of all, our quality control will reduce the quality problem to near zero. If there is a quality problem caused by us, we will send you free goods for replacement or refund your loss.
Q7:How to contact us?
A7: You can choose your interested products and send inquiry to us.You can contact us through WhatsApp directly, you will get our reply.
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