Description of 5-Bromo-7-azaindole from Watson Biotechnology Co., Ltd
Basic Information of 5-Bromo-7-azaindole |
Product Name | 5-Bromo-7-azaindole |
CAS NO. | 183208-35-7 |
Apperance | White powder |
Assay | 99% |
Pacakge | 1kg/Foil Bag,25kg/Drum/Box |
MOQ | 1kg |
Storage | Cool and dry place |
Shelf Life | 2 Years |
Brand | Watson |
Application of 5-Bromo-7-azaindole CAS 183208-35-7 use for Pharmaceutical Discovery and Synthetic Organic Chemistry
5-Bromo-7-azaindole is a brominated heterocyclic compound, structurally similar to indole, with a nitrogen atom replacing one of the carbons in the ring. It has several applications, particularly in organic chemistry, drug discovery, and materials science:
### 1. **Pharmaceutical and Drug Discovery**:
- **Lead Compound for Drug Development**: It is used as a building block or intermediate in the synthesis of biologically active compounds, particularly in medicinal chemistry. Its structure resembles the core of many bioactive molecules, making it a useful starting point for drug design, especially in the areas of kinase inhibitors and other enzyme-targeting drugs.
- **Fragment-based Drug Discovery (FBDD)**: 5-Bromo-7-azaindole is often used in FBDD, where small molecular fragments are screened for binding to biological targets. The indole-like structure allows for interaction with a variety of protein active sites, while the bromine atom can serve as a point for further functionalization.
### 2. **Synthetic Organic Chemistry**:
- **Cross-Coupling Reactions**: The bromine atom in 5-Bromo-7-azaindole makes it a useful substrate for cross-coupling reactions (e.g., Suzuki, Stille, or Sonogashira couplings). This allows for the formation of complex molecules by linking different organic fragments.
- **Heterocyclic Synthesis**: Its azaindole structure is a useful motif in the synthesis of more complex heterocyclic systems. Such heterocycles are common in biologically active molecules.
### 3. **Materials Science**:
- **Organic Electronics**: Derivatives of 5-Bromo-7-azaindole may be used in the design and synthesis of organic semiconductors and other materials for electronic applications, such as organic light-emitting diodes (OLEDs) and organic photovoltaics.
### 4. **Chemical Biology**:
- **Probe Development**: It can be modified to develop chemical probes to study biological processes. The indole core can interact with various biomolecules, and the bromine allows for easy modification to tune its biological activity.
In summary, 5-Bromo-7-azaindole is valuable for developing new pharmaceuticals, materials, and tools for chemical biology due to its versatile reactivity and bioactivity potential.
FAQ From Watson Biotechnology Co., Ltd |
Q | Can I get a sample for free ? |
A | For small QTY and low value product, we can provide sample for free exclude shipping cost. For high value sample, we will charge the basic sample cost, but we can refund all the cost if customers place order after sample test. |
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Q | How to confirm the product quality before placing orders ? |
A | Most of our products confirm to international standards like USP/EP/BP/JP/CP. We will provide COA/TDS/MSDS for customers to confirm the specification before placing order. |
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Q | What is the payment you accept? |
A | For small and low value order, we accept CreditCard, MaterCard,VISA,Western Union and T/T.For large order, we can do T/T and L/C. Any pay on delivery or pay-after are not available for us. |
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Q | What is your shipment way ? |
A | For less than 100kg gross weight order will ship with courier like FedEx or UPS, we support customers to place courier orders remotely by their account, we will package the goods well and wait for pick up.For more than 100kg goods, we will transport by Air or Sea according to customers' requirement. |
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Q | How long is your after-sales service? |
A | We accept customer’s quality complaint in three month after customer received the goods. We provide tech.support for all-life if customer place order from our company. |
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Q | How do you treat quality complaint ? |
A | We support customer to provide our products to any rightful third party testing organization to test our products according to the COA specification, if the test result is confirm with COA, we will take all the loss for customers. |
Watson Biotechnology Co., Ltd is a professional manufacturer which provide 5-Bromo-7-azaindole with good quality and best price, welcome to contact us to get COA/TDS/MSDS of 5-Bromo-7-azaindole.
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