3-?Isoquinolinecarboxyl?ic acid, 4-?hydroxy-?1-?methyl-?7-?phenoxy-?, ethyl ester NEW

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Min. Order1kg
Purity99%
Cas No1809286-36-9
Supply Ability200kg
Update time2023-11-01

Hangzhou ICH Biofarm Co., Ltd

2YR

China

Since2006-07-19

Address1306 Block A, Dragon Times Building, 18 Wantang Road, Hangzhou,310013 CHINA

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Chemical Properties

Product Name	3-?Isoquinolinecarboxyl?ic acid, 4-?hydroxy-?1-?methyl-?7-?phenoxy-?, ethyl ester
CAS No	1809286-36-9
EC-No
Min. Order	1kg
Purity	99%
Supply Ability	200kg
Release date	2023/11/01

3-Isoquinolinecarboxylic acid, 4-hydroxy-1-methyl-7-phenoxy-, ethyl ester

It is a chemical compound with the molecular formula C19H17NO4 and the molecular weight 323.34258 g/mol.

It is an intermediate for the synthesis of roxadustat, a drug for the treatment of anemia in chronic kidney disease (CKD) patients.

Roxadustat is a small molecule inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PH), which stabilizes HIF and activates the transcription of erythropoietin (EPO) and other genes involved in erythropoiesis and iron metabolism .

Roxadustat has been approved in China for both dialysis-dependent and non-dialysis-dependent CKD patients, and is undergoing clinical trials in other countries.

Email: pharmchem1@ichemie.com

Tel&Whatsapp:+86-18771921569

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Company Profile Introduction

Our company specializes in the research, development and production of APIs and pharmaceutical intermediates. At the same time, our core R&D team has more than 20 years of drug R&D experience. Under the support of a good research and development environment and a professional technical team, our company has obtained rich experience and outstanding achievements of new drugs and generic drugs projects. On the one hand, we are focused on the research and development and the optimization of production processes of generic drugs such as anti-viral and anti-malaria. On the other hand, we are also committed to the cooperative development of innovative drugs in the fields of respiratory system and hypoglycemia. We can provide technical support in all key links of drug research and development for drug production and distribution companies.