1-Hydroxybenzotriazole CAS 80029-43-2 supplier in China

1-Hydroxybenzotriazole details 

1-Hydroxybenzotriazole is a coupling reagent used to synthesize amides by the condensation reaction between the activated ester/acid and the amino group of protected amino acids. It is also used as a racemization suppressor during peptide synthesis.

Application 

1-Hydroxybenzotriazole hydrate can be used as a condensation reagent to prepare:

• Poly-γ-glutamic acid methyl ester from a dimer of γ-glutamic acid.

• Oxadiazoles via cyclo condensation of amidoximes with trifluoroacetic anhydride or benzoic acid derivatives.