25C-NBOH (hydrochloride)

2C-C is a 2,5-dimethoxyphenethylamine with a chlorine atom at the four position of the aromatic ring. A known hallucinogen, this compound stimulates monoamine receptor activity while inhibiting the re-uptake of serotonin and norepinephrine.^1,2 25C-NBOH is a derivative of 2C-C having an N-(2-hydroxybenzyl) addition at the amine. It is a potent agonist of serotonin receptors that shows selectivity for 5-HT_2A over 5-HT_2C (EC₅₀s = ~ 0.40 and 15 nM, respectively).³ This product is intended for forensic and research applications.

25C-NBOH (Hydrochloride) is a derivative o f 25C-NBOH (CAS# 88441-15-0) which is a hallucinogen that stimulates monoamine receptor activities and at the same time inhibits the re-uptake of serotonin (CAS# 153-98-0) and norepinephrine. Intended for forensic and research use.

1. Nonaka, R., Nagai, F., Ogata, A., et al. In vitro screening of psychoactive drugs by [35S]GTPγS binding in rat brain membranes Biol. Pharm. Bull. 30(12),2328-2333(2007).
2. Nagai, F., Nonaka, R., and Satoh Hisashi Kamimura, K. The effects of non-medically used psychoactive drugs on monoamine neurotransmission in rat brain Eur. J. Pharmacol. 559(2-3),132-137(2007).
3. Hansen, M., Phonekeo, K., Paine, J.S., et al. Synthesis and structure-activity relationships of N-benzyl phenethylamines as 5-HT_2A/²C agonists ACS Chem. Neurosci. 5(3),243-249(2014).