2-(4-HYDROXY-3-METHOXYPHENYL)BENZOTHIAZOLE

Chemical Properties

storage temp.	2-8°C
solubility	DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:9): 0.1 mg/ml; Ethanol: 1 mg/ml
form	A crystalline solid
color	Light yellow to yellow

Cell Line:
Concentration:	0.001, 0.01, 0.1, 1, 10 μM
Incubation Time:	96 hours
Result:	Strongly inhibited cell proliferation of MCF-7 and MDA-MB-231 cells in a dose-dependent manner (IC ₅₀ =85.8 nM and 4.02 μM, respectively).

Animal Model:	BALB/cAjcl-nu/nu female mice (4-5 weeks) inoculated with MCF-7 or MDA-MB-231 cells
Dosage:	15 mg/kg
Administration: < /td>	Sc every 2 days for 63 days
Result:	Suppressed tumor growth in mice injected with MCF-7 and MDA-MB-231 cells.