Bax is a tumor suppressor that belongs to the Bcl-2 family and modulates cellular apoptosis. Bax is regulated by p53 and increased Bax levels have been associated with cell death stimuli. Alterations in Bax have been linked to several neurological diseases and cancers . Monoclonal Anti-Bax antibody is specific for the epitope within amino acids 3-16 of the human Bax protein. The antibody reacts with Bax in bovines and humans, but not in mice and rats.
