4-HYDROXY-2-[(1E)-[4-(1-METHYLETHYL)PHENYL]METHYLENE]HYDRAZIDE
101574-65-6 Basic informationMore
- Product Name:4-HYDROXY-2-[(1E)-[4-(1-METHYLETHYL)PHENYL]METHYLENE]HYDRAZIDE
- Synonyms: (E)-4-hydroxy-N'-(4-isopropylbenzylidene)benzohydrazide 4-Hydroxybenzoic acid 2-[[4-(1-methylethyl)phenyl]methylene]hydrazide 4-HYDROXY-2-[(1E)-[4-(1-METHYLETHYL)PHENYL]METHYLENE]HYDRAZIDE 2-[[4-(1-Methylethyl)phenyl]methylene]hydrazide 4-hydroxybenzoic acid 4-hydroxy-N'-(4-isopropylbenzylidene)benzohydrazide CS-1084 Benzoic acid, 4-hydroxy-, 2-[[4-(1-methylethyl)phenyl]methylene]hydrazide 4-hydroxy-N'-(4-isopropylphenyl‐ methylidene)-benzohydrazide
- CAS:101574-65-6
- MF:C17H18N2O2
- MW:282.34
- EINECS:
- Mol File:101574-65-6.mol
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USE
The estrogen-related receptors (ERRs) are orphan nuclear receptors with homology to the estrogen receptor family and are expressed in tissues with high metabolic demand. Binding of peroxisome proliferator-activated receptor γ-coactivator 1α (PGC-1α) to this class of receptors is known to potentiate ERR activity. GSK4716 is an ERRβ/γ agonist (IC50 = 2 μM) that can activate the receptor with similar potency as the protein ligand, PGC-1α. It is more than 50-fold selective for binding to ERRβ/γ compared with the estrogen receptors. This compound has been used to demonstrate the contribution of ERR receptor activity to the regulation of mitochondrial activity in skeletal muscle during exercise.[Cayman Chemical]
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- Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel:821-50328103-801 18930552037
- Products Intro:Product Name:GSK 4716;4-Hydroxy-2-[(1E)-[4-(1-Methylethyl)phenyl]Methylene]hydrazide
CAS:101574-65-6
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g More... - CB Index:69
- Related Information:Catalog(15848)
- Company Name:ZHIWE CHEMTECH CO LTD
- Tel:021-20221225 13917446399
- Products Intro:Product Name:GSK 4716
CAS:101574-65-6
More... - CB Index:61
- Related Information:Catalog(624)
- Company Name:Nanjing Chemlin Chemical Co., Ltd
- Tel:025-83697070
- Products Intro:Product Name:4-Hydroxybenzoic acid 2-[[4-(1-methylethyl)phenyl]methylene]hydrazide
CAS:101574-65-6
Purity:98% Package:5KG; 1KG More... - CB Index:64
- Related Information:Catalog(19116)
- Company Name:Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
- Tel:025-66099280 17798518460
- Products Intro:Product Name:GSK-4716
CAS:101574-65-6
Purity:95% Package:1g;5g;10g More... - CB Index:55
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- Company Name:Shanghai Lollane Biological Technology Co.,Ltd.
- Tel:021-52996696，15000506266 15000506266
- Products Intro:Product Name:GSK4716
CAS:101574-65-6
Purity:98% HPLC Package:5mg，10mg，50mg，100mg，1g，5g - CB Index:55
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