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kijanimicin

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78798-08-0 Basic informationMore
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Kijanimicin is a tetronic acid related to saccharocarcin, chlorothricin, versipelostatin and tetrocarcin. Like the tetrocarcins, kijanimicin contains an unusual nitroaminoglycoside. Kijanimicin is a potent antibacterial, antimalarial and antitumor active. Several members of this class have received considerable literature focus. Versipelostatin inhibits transcription from the promoter of GRP78, a gene that is activated as part of a stress signalling pathway under glucose deprivation resulting in unfolded protein response (UPR). The UPR-inhibitory action is seen only in conditions of glucose deprivation and causes selective and massive killing of the glucose-deprived cells. Tetrocarcin A appears to target the phosphatidylinositide-3'-kinase/Akt signalling pathway.

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  • Company Name:Lynnchem
  • Tel:86-(0)29-85992781 17792393971
  • Products Intro:Product Name:kijanimicin
    CAS:78798-08-0
    Purity:>99% by HPLC Package:1mg;5mg More...
  • CB Index:58
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  • Company Name:Shenzhen Polymeri Biochemical Technology Co., Ltd.
  • Tel:+86-400-002-6226
  • Products Intro:Product Name:Kijanimicin
    CAS:78798-08-0
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  • CB Index:58
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  • Company Name:Zhejiang Huida Biotech Co., LTD
  • Tel:0571-89903882 13626641628
  • Products Intro:Product Name:Kijanimicin
    CAS:78798-08-0
    Purity:99% HPLC Package:10mg;100mg;1g;10g;100g
  • CB Index:58
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  • Company Name:MedBioPharmaceutical Technology Inc
  • Tel:021-69568360 18916172912
  • Products Intro:Product Name:kijanimicin
    CAS:78798-08-0
    Purity:98% Package:500ug; 2.5mg Remarks:Medbio
  • CB Index:58
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