PAI-1 Price
Product number | Packaging | Price | Product description | Buy |
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Sigma-Aldrich 528205 | 50μg | $390 | Plasminogen Activator Inhibitor-1, Human, Recombinant The Plasminogen Activator Inhibitor-1, Human, Recombinant controls the biological activity of Plasminogen Activator. This small molecule/inhibitor is primarily used for Protease Inhibitors applicatio |
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Usbiological 027470 | 96Tests | $706 | Plasminogen Activator Inhibitor 1 |
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Usbiological 156349 | 10ug | $333 | Plasminogen Activator Inhibitor 1 |
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Usbiological 027469 | 96Tests | $851 | Plasminogen Activator Inhibitor 1 |
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Usbiological P4256-38 | 1Kit | $1042 | Plasminogen Activator Inhibitor Type 1, Mouse Assay Kit, BioAssay™ |
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PAI-1 Chemical Properties,Usage,Production
Enzyme inhibitor
This 402-residue serine protease inhibitor, or serpin (MW = 45074 g/mol; Abbreviation: PAI-1) binds to and inhibits plasminogen activators-tissuetype plasminogen activator (tPA) and urokinase-type plasminogen activator (uPA). This inhibition reduces plasmin production and suppresses dissolution of fibrin clots. Elevated PAI-1 levels correlate with an increased cardiovascular disease risk, a behavior that has also been linked to obesity and metabolic syndrome. Pharmacological suppression of PAI-1 is a likely way to prevent or treat vascular disease. Reduced PAI-1 levels may result in increased fibrinolysis and an associated bleeding diathesis. PAI-1 was initially identified in the 1980s, and the first reported case of PAI-1 deficiency appeared in 1989. Unambiguous proof that PAI-1 deficiency as a cause of a bleeding disorder has been rare, but use of selective PAI inhibitors (See PAI-749) may clarify this point. Because of lack of standardized commercially available PAI-1 activity assay sensitive in the lowest range, the true prevalence of this rare condition has yet to be established.Preparation Products And Raw materials
PAI-1 Suppliers
Global(34)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
021-34661275 15301693058 |
yajikit@163.com | China | 9592 | 58 | |
021-60345367 13916550749 |
sales@shzbio.com | China | 9966 | 58 | |
-- | sales@advtechind.com | United States | 6106 | 58 |
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