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Piroxicam Structure

Piroxicam

Chemical Properties

Melting point 198-200°C
Density  1.3664 (rough estimate)
refractive index  1.6320 (estimate)
storage temp.  2-8°C
solubility  Practically insoluble in water, soluble in methylene chloride, slightly soluble in anhydrous ethanol. It shows polymorphism (5.9).
form  Solid
pka 6.3 (2:1 dioxane-water)
color  White to Light yellow
Water Solubility  Soluble in water, ethanol, chloroform, ethyl acetate.
λmax 358nm(H2O)(lit.)
Merck  14,7506
BCS Class 2
InChIKey QYSPLQLAKJAUJT-UHFFFAOYSA-N
CAS DataBase Reference 36322-90-4(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 13T4O6VMAM
NCI Drug Dictionary Feldene
ATC code M01AC01,M02AA07,S01BC06
NIST Chemistry Reference Piroxicam(36322-90-4)
EPA Substance Registry System 2H-1,2-Benzothiazine-3-carboxamide, 4-hydroxy-2-methyl-N-2-pyridinyl-, 1,1-dioxide (36322-90-4)

Safety

Symbol(GHS)
Signal wordDanger
Hazard statements H301-H373
Precautionary statements P260-P264-P270-P301+P310-P314-P405
Hazard Codes  Xn,F,T
Risk Statements  22-25
Safety Statements  26-36
RIDADR  UN 2811
WGK Germany  3
RTECS  DL0705000
HazardClass  6.1(b)
PackingGroup  III
HS Code  29349990
Toxicity LD50 orally in mice: 360 mg/kg (Wiseman)
NFPA 704:
0
2 0

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