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304-20-1

Name Hydralazine hydrochloride
CAS 304-20-1
EINECS(EC#) 206-151-0
Molecular Formula C8H9ClN4
MDL Number MFCD00135998
Molecular Weight 196.64
MOL File 304-20-1.mol

Chemical Properties

Appearance White Crystalline Solid
Melting point  273°C
Boiling point  322.13°C (rough estimate)
density  1.2961 (rough estimate)
refractive index  1.6110 (estimate)
storage temp.  -20?C Freezer
solubility  Soluble in water, slightly soluble in ethanol (96 per cent), very slightly soluble in methylene chloride
form  neat
color  White to Almost white
PH pH (20g/l, 25℃) : 3.5~4.5
Stability: Stable. Incompatible with strong oxidizing agents.
Water Solubility  Soluble in water. Slightly soluble in diethyl ether and alcohol.
Usage Inhibits DNA methyltransferase and modulates epigenetic regulation of gene expression. Non-selective MAO-A/B inhibitor; semicarbazide sensitive amine oxidase inhibitor. Antihypertensive
Merck  14,4763
BRN  3568329
BCS Class 3
Contact allergens
Hydralazine is a hydrazine derivative used as a antihypertensive drug. Skin rashes have been described during treatment. Exposure occurs mainly in the pharmaceutical industry. Cross-sensitivity is frequent with hydrazine, which is considered to be a potent sensitizer.
InChIKey ZUXNZUWOTSUBMN-UHFFFAOYSA-N
CAS DataBase Reference 304-20-1(CAS DataBase Reference)
EPA Substance Registry System 304-20-1(EPA Substance)

Safety Data

Hazard Codes  Xn
Risk Statements 
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin .
Safety Statements 
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS  TH9000000
TSCA  Yes
HazardClass  6.1
PackingGroup  III
HS Code  29339900
Hazardous Substances Data 304-20-1(Hazardous Substances Data)
Toxicity
LD50 oral in rat: 280mg/kg

Hazard Information

Material Safety Data Sheet(MSDS)

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