184845-43-0

Name	1-[3-(9H-CARBAZOL-9-YL)PROPYL]-4-(2-METHOXYPHENYL)-4-PIPERIDINOL HYDROCHLORIDE
CAS	184845-43-0
Molecular Formula	C27H30N2O2
MDL Number	MFCD00952020
Molecular Weight	414.54
MOL File	184845-43-0.mol

Synonyms

NNC 05-2090HCl NNC 05-2090 HYDROCHLORIDE 1-[3-(9H-CARBAZOL-9-YL)PROPYL]-4-(2-METHOXYPHENYL)-4-PIPERIDINOL HYDROCHLORIDE

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Chemical Properties

storage temp.

Desiccate at RT

Hazard Information

Uses

NNC 05-2090 Hydrochloride is a GABA uptake inhibitor displaying selectivity for BGT-1 (mGAT-2) transporters.

Biological Activity

GABA uptake inhibitor that displays moderate selectivity for BGT-1 (mGAT-2) transporters (K i values are 1.4, 15, 19 and 41 μ M for hBGT-1, hGAT-3, hGAT-1 and hGAT-2 respectively). Anticonvulsive; inhibits sound-induced tonic and clonic convulsions in DBA/2 mice. Also displays affinity at α 1 - and D 2 -receptors (IC 50 values are 266 and 1632 nM respectively).

Supplier

3B Pharmachem (Wuhan) International Co.,Ltd.

Telephone821-50328103-801 18930552037

Websitehttps://www.chemicalbook.com/ShowSupplierProductsList13285/0.htm

Energy Chemical

Telephone021-58432009 400-005-6266

Websitehttp://www.energy-chemical.com

TargetMol Chemicals Inc.

Telephone 4008200310

Websitehttps://www.targetmol.cn/

Nantong QuanYi Biotechnology Co., Ltd

Telephone0513-66337626 18051384581

Websitehttps://www.chemhifuture.com/

Nanjing Tengyi Biotechnology Co., Ltd

Telephone025-58851786 17714337195

Websitehttps://tybiochem.com/

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