172152-50-0

After oral administration, Ilaprazole sodium selectively enters the gastric parietal cells and is converted into an active metabolite of sulfenamide, which interacts with the sulfhydryl group on the H+/K+-ATPase to form a covalent combination of disulfide bonds, irreversibly inhibiting H+/K+- ATPase, which inhibits gastric acid secretion.

Target	Value
Proton pump ()
H(+) /K(+)-ATPase (in rabbit parietal cell preparation)	6 μM

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