149838-22-2

Biological probe for membrane dynamics.

Water Soluble fluorescent RH probe

ChEBI: FM 1-43 dye is an organic bromide salt, a quaternary ammonium salt, a tertiary amine and a pyridinium salt. It has a role as a fluorochrome. It contains a FM 1-43(2+).

MM 1-43 is a cationic dye, equivalent to membrane probe FM 1-43. MM 1-43 is believed to insert into the outer leaflet of the cell membrane where it becomes intensely fluorescent. In a neuron that is actively releasing neurotransmitters, the dye becomes internalized within the recycled synaptic vesicles and the nerve terminals become brightly stained. The staining of cell-surface specific membranes is useful for identifying actively firing neurons and for investigating the mechanisms of activity-dependent vesicle cycling. Wavelength Maxima: Excitation 510nm, Emission 626nm