Hazard
Irritating to skin, eyes.
Chemical Properties
Colorless to light yellow liqui
Uses
4-Chlorobenzyl Chloride is a benzylchloride derivative used in the preparation of various biologically active compounds such as bronchodilators and antibacterial agents.
Uses
Reagent used in derivatization of, for example, a calix[4]arene1 and a tryptamine.2
General Description
4-Chlorobenzyl chloride is generally used in the preparation of quaternary ammonium salts. It acts as an intermediate in the production of rice herbicide, pharmaceuticals and pesticides.
Purification Methods
Dry it over CaSO4, then fractionally distil it under reduced pressure. Crystallise it from heptane or dry diethyl ether at low temperature. [Beilstein 5 IV 816.] LACHRYMATORY.