1030937-27-9

Losartan-D4 is a deuterium-labeled version of Losartan, which is an angiotensin II receptor antagonist that competes with the binding of angiotensin II to AT1 receptors with an IC50 of 20 nM. Losartan is an antagonist of the angiotensin (AT) II receptor subtype AT1 with a K i value of 5-20 nM. 

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As a labelled version of Losartan, Losartan-d4 can be used as a nonpeptide angiotensin II AT1-receptor antagonist and Antihypertensive.

Losartan-d4 can be intended for use as an internal standard for the quantification of Losartan by GC- or LC-mass spectrometry.